LuLuLun medicated masks (薬用ルルルン) are the two quasi-drug (医薬部外品) sheet masks from Japanese face-mask brand LuLuLun: they contain active ingredients approved in Japan for specific claims, such as preventing rough skin and acne. There are two: Skin Conditioning & Moisturizing (保湿スキンコンディション) for sensitive skin and dryness, with dipotassium glycyrrhizate, and Acne Care & Whitening (美白アクネ), which adds tranexamic acid. Each comes as four individually wrapped sheets for ¥1,650 on LuLuLun’s official Japanese shop. This guide compares both, based on LuLuLun’s official Japanese pages.

What you’ll learn in this article:

  • What makes LuLuLun’s medicated masks different from its daily lotion masks
  • Skin Conditioning & Moisturizing vs Acne Care & Whitening: actives, ingredients and price
  • The full ingredient list of each mask
  • How long to leave each one on, and how often to use it
  • How to buy LuLuLun medicated masks from Japan

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What Are LuLuLun Medicated Masks?

LuLuLun medicated masks are LuLuLun’s first quasi-drug series: sheet masks with active ingredients approved in Japan for specific claims, which LuLuLun describes as “face supplements” you apply. Unlike LuLuLun’s daily lotion masks, they are special-care masks that LuLuLun recommends once or twice a week on top of your usual skincare, for times when your skin is having trouble or before an important day. LuLuLun says they suit any skin type, age and season.

Skin Conditioning & Moisturizing vs Acne Care & Whitening

Pick Skin Conditioning & Moisturizing if your skin is sensitive and dry, and Acne Care & Whitening if you want to prevent acne as well as dark spots and freckles. Both help prevent rough skin and acne with dipotassium glycyrrhizate; only Acne Care & Whitening adds tranexamic acid, and it stays on for 5 minutes instead of 15 to 30.

Skin Conditioning & MoisturizingAcne Care & Whitening
Japanese name薬用ルルルン 保湿スキンコンディション薬用ルルルン 美白アクネ
Made for (LuLuLun)Sensitive skin prone to rough patches from dryness; dryness; calming inflammationPreventing acne; preventing dark spots and freckles; dullness caused by dryness
Active ingredientsDipotassium glycyrrhizate (anti-inflammatory)Tranexamic acid (whitening), dipotassium glycyrrhizate (anti-inflammatory)
Time on face15 to 30 minutes5 minutes
How oftenOnce or twice a weekOnce or twice a week
Pack and price in Japan4 sheets (26 mL each), ¥1,6504 sheets (23 mL each), ¥1,650

From LuLuLun’s official Japanese product pages and series page (as of October 2026; prices after LuLuLun’s 1 October 2026 price revision). “Whitening” here is the approved quasi-drug claim of suppressing melanin production to prevent dark spots and freckles.

LuLuLun Medicated Skin Conditioning & Moisturizing: The Sensitive Skin Mask

LuLuLun Medicated Skin Conditioning & Moisturizing (薬用ルルルン 保湿スキンコンディション) is the mask for sensitive skin, which LuLuLun defines as skin that has become prone to rough patches because of dryness. Its active ingredient, dipotassium glycyrrhizate from licorice, is an anti-inflammatory that LuLuLun says helps prevent rough skin and acne. LuLuLun builds its supporting ingredients around three steps: calm, strengthen and moisturise.

LuLuLun medicated mask for sensitive skin and moisture, box and pouch (薬用ルルルン 保湿スキンコンディション)
© Dr.LuLuLun Inc.

Lavender and edelweiss extracts

Ingredients that LuLuLun lists as helping prevent rough skin.

Ginseng extract

A skin-conditioning ingredient that LuLuLun says helps prevent rough skin.

Ceramide 3 (NP) and sorbitol ferment polysaccharide

Moisturising ingredients; LuLuLun calls the plant-based ferment a moisturiser for sensitive skin.

The sheet is made from a pure-cotton-derived material that LuLuLun says absorbs and holds plenty of essence and wraps gently around the skin.

Full ingredients (Skin Conditioning & Moisturizing): Active ingredient: dipotassium glycyrrhizate. Other ingredients: concentrated glycerin, 1,3-butylene glycol, sorbitol ferment polysaccharide, N-stearoyl phytosphingosine (ceramide 3), edelweiss extract, lavender extract, ginseng extract, carboxyvinyl polymer, xanthan gum, polyoxyethylene hydrogenated castor oil, methylparaben, potassium hydroxide, disodium edetate, purified water.

LuLuLun Medicated Acne Care & Whitening: The Acne Mask with Tranexamic Acid

LuLuLun Medicated Acne Care & Whitening (薬用ルルルン 美白アクネ) is the mask for preventing acne, and dark spots and freckles. It has two active ingredients: dipotassium glycyrrhizate, an anti-inflammatory, and tranexamic acid, a whitening active that LuLuLun says suppresses melanin production to prevent dark spots and freckles. LuLuLun says it helps prevent rough skin and acne for a healthy, clear look. Its Japanese name, 美白アクネ, reads literally as “Whitening Acne”, and some overseas retailers list it as “Brightening Acne Care”.

LuLuLun medicated mask for acne and whitening, box and pouch (薬用ルルルン 美白アクネ)
© Dr.LuLuLun Inc.

Mulberry and kiwi extracts

Ingredients that LuLuLun lists for firmness and gloss.

Rose fruit and peony extracts

Tightening and skin-conditioning ingredients that LuLuLun says help prevent rough skin.

The sheet is a smooth, high-density sheet made from natural materials, which LuLuLun says is gentle on acne-prone skin.

Full ingredients (Acne Care & Whitening): Active ingredients: tranexamic acid, dipotassium glycyrrhizate. Other ingredients: concentrated glycerin, 1,3-butylene glycol, kiwi extract, mulberry extract, rose fruit extract, peony extract, carboxyvinyl polymer, xanthan gum, polyoxyethylene hydrogenated castor oil, methylparaben, anhydrous citric acid, sodium citrate, potassium hydroxide, sodium metabisulfite, disodium edetate, purified water.

Ingredient lists as published by LuLuLun (checked October 2026), in the quasi-drug labelling format used in Japan. The English names are our translations of LuLuLun’s Japanese labelling names. Formulas can change, so always check the package.

How to Use LuLuLun Medicated Masks

Use a LuLuLun medicated mask after washing your face, once or twice a week on top of your usual routine. Leave Skin Conditioning & Moisturizing on for 15 to 30 minutes, and Acne Care & Whitening for 5 minutes only.

  1. With clean hands, take one sheet out of its pouch and use it straight away.
  2. Fit the eye and mouth openings to your face.
  3. Leave it on for the time above: 15 to 30 minutes for Skin Conditioning & Moisturizing, or 5 minutes for Acne Care & Whitening.
  4. Take it off, fold it and wipe your face with it, then pat in the essence.
  5. Finish with a milk or cream.

LuLuLun recommends a patch test on the inside of your arm first if you’re using it for the first time or your skin reacts easily, and says not to use it on wounds, swelling or eczema.

LuLuLun Medicated Masks vs Daily LuLuLun Masks

The difference is how often you use them: LuLuLun medicated masks are quasi-drugs with approved actives for once- or twice-a-week care, while LuLuLun’s daily masks are cosmetics you use every day in place of toner. LuLuLun’s daily masks include Pure Everys, Precious, OVER45, Hydra and Aura Bright. The medicated masks are quasi-drugs with approved actives, sold four sheets to a pack, for use once or twice a week alongside your usual skincare.

Where to Buy LuLuLun Medicated Masks

The easiest way to get LuLuLun medicated masks outside Japan is to order them from Japan through kachicollect. Buy from the kachicollect catalog with no proxy fees, and if you can’t find the one you want there, search Japanese stores or marketplaces for its Japanese name, 薬用ルルルン 保湿スキンコンディション or 薬用ルルルン 美白アクネ, and paste the product URL into kachicollect for an instant quote, with no request fee. Duties are shown in your total before you pay, and orders ship worldwide with tracking in about 7 to 14 days.

LuLuLun’s official Japanese shop doesn’t ship overseas or accept credit cards issued outside Japan, according to its FAQ. On marketplaces such as eBay, check the Japanese name, because LuLuLun’s other masks for sensitive skin or dullness are not quasi-drugs.

Proxy services that buy from Japanese stores on your behalf are another option, but the service fee they advertise is only the starting point, and various other charges are added on top by the time you check out.

Pay Only the Item Price and Shipping

Buy from the kachicollect catalog with no proxy fees: you pay the listed price plus shipping, and duties are shown before checkout. Can’t find what you want? Paste its URL from any Japanese store or marketplace and get an instant quote, also with no request fee.

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For every LuLuLun series in one place, from daily masks to the cleansing balm, see our LuLuLun guide.

LuLuLun Medicated Mask FAQ

What does “medicated” mean for LuLuLun masks?

It means they are quasi-drugs (医薬部外品) in Japan: they contain active ingredients approved for specific claims, such as preventing rough skin and acne or preventing dark spots and freckles. LuLuLun’s other masks are cosmetics.

Which LuLuLun medicated mask is for acne?

Both help prevent acne, according to LuLuLun, because both contain dipotassium glycyrrhizate. Choose Acne Care & Whitening if you also want to prevent dark spots, or Skin Conditioning & Moisturizing if your skin is sensitive and dry.

Does LuLuLun Acne Care & Whitening contain tranexamic acid?

Yes. Tranexamic acid is one of its two active ingredients, which LuLuLun says suppresses melanin production to prevent dark spots and freckles.

How long do you leave a LuLuLun medicated mask on?

15 to 30 minutes for Skin Conditioning & Moisturizing, and 5 minutes for Acne Care & Whitening.

Can I use LuLuLun medicated masks every day?

LuLuLun recommends them once or twice a week on top of your usual skincare. For daily use, choose one of its lotion masks, such as Pure Everys.

Is the LuLuLun medicated mask good for sensitive skin?

Skin Conditioning & Moisturizing is the one LuLuLun makes for sensitive skin, which it defines as skin that has become prone to rough patches because of dryness, and its sheet is a soft pure-cotton-derived material. LuLuLun still recommends a patch test on the inside of your arm before first use.

Are LuLuLun medicated masks fragrance-free?

Neither mask lists fragrance or ethanol in LuLuLun’s full ingredient list.

Where can I buy LuLuLun medicated masks outside Japan?

LuLuLun’s official shop doesn’t ship overseas, so the simplest way is to order from Japan through kachicollect: no proxy fees, duties shown before you pay, and tracked shipping worldwide.

Do LuLuLun medicated masks contain parabens?

Yes. Both list methylparaben (methyl parahydroxybenzoate) among their other ingredients.

Conclusion: Which LuLuLun Medicated Mask to Choose

Choose LuLuLun Medicated Skin Conditioning & Moisturizing if your skin is sensitive and dry and you want a calming, moisturising treatment, or Acne Care & Whitening if you want to prevent acne and also prevent dark spots and freckles, with tranexamic acid to suppress melanin production. Use either once or twice a week alongside your usual skincare, and for daily care, pair it with one of LuLuLun’s lotion masks such as Pure Everys.

For a weekly serum mask as special care, see our LuLuLun ONE guide.

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